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Kaltenecker, D

NNMT is overexpressed in white adipose tissue in obese individuals, where it consumes S-adenosylmethionine (SAM) the body's primary methyl donor to methylate nicotinamide, effectively draining the methyl pool and reducing NAD+ precursor availability

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Obes Res

NASO B12 NASAL SPRAY is also used to manage adult patients with vitamin B12 deficiency that occurred due to dietary, drug-induced, and/or malabsorption factors