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Given the bidirectional communication between the brain and the skin, referred to as the brainskin axis, the psychological benefits of H 2 may indirectly enhance skin health, particularly under stress-related conditions such as acne, rosacea, or inflammatory dermatoses

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the homogenizer was stopped and the solution was placed on a magnetic plate, covered with parafilm and mixed with a magnetic stir bar until cooled to room temperature

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Hydrogen peroxide can non-selectively oxidize protein amino acids in particular cysteine and methionine rendering proteins inactive and/or amenable to electrophilic modification (Kaspar et al., 2009)