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Proc Natl Acad Sci USA 110:48044809 Madiraju P, Pande SV, Prentki M, Madiraju SR (2009) Mitochondrial acetylcarnitine provides acetyl groups for nuclear histone acetylation

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Thereafter, anhydrous sodium sulfate was added to remove moisture from the product which was then filtered and distilled under reduced pressure to remove ethyl acetate, followed by fractional distillation under reduced pressure (93-95 C/5 mmHg) to obtain 40.4 g (yield: 80 %) of ethyl 4-chloro-3-hydroxybutyrate

(1990): Effect of acetyl-L-carnitine on geriatric patients suffering from dysthymic disorders

In two affected dogs, administering high doses of L-carnitine led to an increase in myocardial L-carnitine levels and significant improvements in both health and heart function

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