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Description
In highly differentiated human CD4 T cells (the CD27CD28 subset), AMPK activation under metabolic stress or DNA damage recruits TAB1 to induce p38 autophosphorylation, leading to telomerase suppression and proliferative arrest 44
Nrf2 activators Nrf2 signaling is implicated in various oxidative stress-related diseases, such as neurodegenerative diseases [209, 210], CVDs [211], diabetes [14], and cancer [212]
Zhao H, Zhang M, Liu Q, et al
Male SpragueDawley (SD) adult rats (200250 g) were purchased from Beijing Vital River Laboratory Animal Technology Co., Ltd
Front Physiol 9:755
In summary, we found that PRKN gene expression contributes to the network of available thiols in the cell, including by parkins participation in glutathione recycling, which involves a reversible, posttranslational modification at select cysteines
