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High-density lipoprotein (HDL) plays a significant role in protecting the BBB from oxidative stress by reducing inflammation and promoting the clearance of ROS [49,50,51]
In fact, scurvy was the leading cause of naval deaths between the 16th and 18th centuries, killing more sailors than all battles, storms and other diseases combined
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Shih AY, Johnson DA, Wong G et al (2003) Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress
doi:10.3238/arztebl.2017.0653 [22] Peckham S, Lowery D, Spencer S
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