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However, subsequent research revealed that HGF and its receptor c-Met are widely expressed in the brain, particularly in the hippocampus, cortex, and cerebellum

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Such changes in gut microbial diversity can compromise the integrity of the epithelial barrier, leading to leaky gut or dysbiosis, in which increased intestinal permeability permits the passage of bacteria, toxins, and metabolites, thereby causing immune activation and intestinal disorders in the fetus [17]