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Its name originates from its recognized activity to cause necrosis in tumors, but it is also involved in the response to bacterial and viral infections

doi: 10.1093/bioinformatics/btu393 23 WuTHuEXuSChenMGuoPDaiZet al

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The study involving breeding hamsters indicated that winter-like melatonin significantly decreased the expression of DNA methyltransferases in hypothalamus, followed by the hypomethylation of the dio3 promoter responsible for gonadal regression [124]

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doi: 10.1159/000527213 137 BowmanSJFoxRDornerTMarietteXPapasAGrader-BeckTet al
