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Description
Inflammatory mediators of peripheral origin (such as cytokines) can enter the central nervous system through permeable regions of the blood-brain barrier or via active transport, where they activate microglia and exacerbate neuroinflammation ( Studies have shown that resveratrol (RES) (30 mg/kg, once every 3 days for 3 months) improves motor dysfunction and peripheral immune dysregulation in an -Syn A53T transgenic PD mouse model
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2022;10:e13992
[DOI] [PubMed] [Google Scholar] Rapp J
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