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Depending on the subcellular localization of bacteria, two types of regulation may occur ( Regulated proteolysis and the optimum pH are required by the bacterial virulence factors to easily execute the cell-cell spread, causing the least damage to the host cell otherwise caused by listeriolysin- O cytotoxicity ( Both the phospholipases, plcA and plcB, have overlapping functions in the pathogenesis of L

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An ideal analytical tool for lipidomics in order to survey a wide range of lipids in discovery work should not only provide detailed information at multiple lipid structure isomer levels (e.g., C=C location/geometry and sn -position), but also be feasible for large-scale quantitative analysis