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This type of drug interaction may also reduce the rate of generation of toxic metabolites

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Cytoprotective role of heme oxygenase-1 in cancer chemoresistance: focus on antioxidant, antiapoptotic, and pro-autophagy properties

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It has been established that astrocytes are key to CNS metabolism of GSH, but further research is also required to explore the correlation between GSH levels in astrocytes and overall GSH content in the brain (Dringen and Arend, 2025)
