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Nanoscale 13(4):22662285

Florance I, Ramasubbu S

In muscle of GPx1 knockout mice, Akt phosphorylation was increased following exposure of fasted mice to an insulin injection, presumably owing to increased production of hydrogen peroxide caused by GPx1 deficiency [97]

The North American Menopause Society (NAMS, 2022) and ACOG now recognize that for healthy women under 60 particularly within 10 years of menopause HRT may offer protective effects for bone, heart, and cognitive health, beyond symptom relief

Authors also thank the Slovak Grant Agencies VEGA Project 1/0542/24 and Project APVV 190087

Ethics approval and consent to participate statement All methods were performed in accordance with the relevant guidelines and regulations and all procedures involving animal research were approved by the Animal Care and Use Committee of the University of Western Ontario (Protocol number: 2022-119)