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Most rat studies use intraperitoneal injection (directly into the abdominal cavity)
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10.3390/microorganisms12050873 150 ZhangY.TanL.LiC.WuH.RanD.ZhangZ
Associated with that, they demonstrated alterations in synaptic processes in the myenteric plexus and dendritic spines in the hippocampus, which correlated with a reduction in BDNF at both sites
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