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Introduction Reactive oxygen and nitrogen species are generated by endogenous and exogenous processes, while enzymatic and non-enzymatic antioxidants neutralize them

This is an important finding as opioid-injecting participants represent a high-risk and difficult-to-treat population

Upregulation or dysregulation of enzymes such as NADPH oxidase, xanthine oxidase, and cytochrome P450 also contributes significantly to elevated ROS levels in cancer cells [94]

Physical pain and associated clinical characteristics in treatment-seeking patients in four substance use disorder treatment modalities

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Potterton, L
