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We evaluated the efficacy of genetic (C/EBP- LIP induction) and pharmacological strategies (lysosome and proteasome inhibitors), in restoring the ER-dependent and immunogenic-dependent cell death induced by doxorubicin, in vitro and in syngeneic mice bearing chemoresistant TNBC

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Owing to its rare occurrence, even the most renowned clinical cancer centers do not have a large enough cohort of oral melanoma cases to reliably and significantly correlate the histologic findings with prognosis

The site is situated well within the prehistoric Hohokam region (Pinter 2004), along the southern boundary of traditional pre-reservation Yavapai lands (Khera and Mariella 1983), and upstream from a Depression-era Euroamerican homestead along the Agua Fria River (Ayres and Seymour 1990)