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If you ingest more of this nutrient than your body requires, the excess amount should be excreted in your urine

The benefit comes from replacing whats missing, not from extra B12 on top of normal levels

Besides age, certain indications can increase the risk of vitamin B12 deficiency if you have it: Atrophic gastritis is a condition when your stomach lining is thin

Another RCT found a decrease in homocysteine with 1000 g hydroxo-B12 monthly for 3 months by 2 mol/l, whilst the control group had a 2 mol/l increase, although the difference was not statistically significant