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In PD patients, nearly 80% loss of CP ferroxidase activity in the SN may lead to pro-oxidative iron accumulation, as evidenced by CP knockout mice developing parkinsonian symptoms reversible by iron chelation (56)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 195.Lpez-Sanromn A, Esplugues JV, Domnech E

Ortega RM, Mena MC, Faci M, Santana JF, Serra-Majem L: Vitamin status in different groups of the Spanish population: a meta-analysis of national studies performed between 1990 and 1999

The effect of ophiopogonin C in ameliorating radiation-induced pulmonary fibrosis in C57bl/6 mice: an update study

Hepatic encephalopathy in chronic liver disease: 2014 Practice Guideline by the American Association for the Study of Liver Diseases and the European Association for the Study of the Liver