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The bioavailability of vitamin C is high at lower doses as shown below, but drops to less than 50% at higher doses

[DOI] [PMC free article] [PubMed] [Google Scholar] 113.Cla B, Ga A, Ywa C, et al

Be Active: Aerobic exercise, strength training, and yoga all help build glutathione levels as well as boost your immune system and support detoxification

PMID: 28468797