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In a previous study, transcriptomic profiling of brain regions involved in the brains reward circuitry (prefrontal cortex, dorsal striatum, nucleus accumbens, basolateral amygdala, ventral hippocampus, and ventral tegmental area) revealed considerable changes in transcript expression during the cocaine self-administration, withdrawal, and relapse phases, with the greatest changes detected in the re-exposure phase 40

Effect of sofosbuvir and ribavirin treatment on peripheral and hepatic lipid metabolism in chronic hepatitis C virus, genotype 1-infected patients

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A thermophilic lipase from Burkholderia ubonensis SL-4, has an optimal temperature at 65 C, and maintains good stability when held at 5055 C (Yang et al., 2016)