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Glycogen depletion itself leads to the reduction of glucose for its use in the synthesis of ATP plus lactate accumulation, which induced metabolic acidosis ( Mitochondrial dysfunction will lead to abnormality in energy metabolism processes

Both sites are equally effective for drug delivery

Lucchesi et al., 2004

Pak J Pharm Sci 31(2):411419 Bagheri H, Ghasemi F, Barreto GE, Rafiee R, Sathyapalan T, Sahebkar A (2020) Effects of curcumin on mitochondria in neurodegenerative diseases

[30-33] A plant-based diet is believed to protect against chronic oxidative stress-related diseases
Keto Diet for Autoimmune Disease: A Broader Look It is worth noting that keto's anti-inflammatory effects and glutathione-boosting properties are genuinely beneficial for autoimmunity broadly
