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doi: 10.1016/s0140-6736(75)90856-9

Clinical and translational results of a phase II, randomized trial of an Anti-IGF-1R (Cixutumumab) in women with breast cancer that progressed on endocrine therapy

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This hexapeptide stimulates growth hormone release through the ghrelin receptor, creating GH spikes 4-5 times above baseline levels within 15-30 minutes of injection