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Description
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The diminished removal of cellular components encourages post-translational modification and consequent generation of novel epitopes that stimulate inflammation
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Stripped of any IGF-1 triggers, it lets scientists study how cells break down stored lipids and channel energy, all in tightly controlled adipocyte and metabolic assays

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Eligible patients were required to be 18 years of age or older with NF1 and symptomatic, inoperable PN
