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Description
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[1] Because intrinsic-factor-dependent uptake in the distal ileum can be absent in conditions such as autoimmune gastritis, pancreatic insufficiency, or bariatric surgery, the intramuscular or subcutaneous route bypasses gastrointestinal barriers and reliably restores serum concentrations

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That step prevents one of the most common bench errors: switching to a fresh vial and forgetting that it was reconstituted to a different final volume than the last one
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