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According to studies involving NAFLD patients, approximately 30% of hepatic steatosis cases evolve into steatohepatitis [3], which inevitably progresses to fibrosis and later to cirrhosis [21]

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NAD + precursor therapies include a suite of different formulations involved in either its synthesis or recycling (niacin, niacinamide, nicotinamide mononucleotide, nicotinamide riboside, etc), the optimal of which for mitochondrial disease is not currently known

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Marzo A, Cardace G, Corbelletta C, Pace S, D'Iddio S, Verrotti C et al

Antioxidant action of carnitine: Molecular mechanisms and practical applications