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Treatment groups (Tyr, Cys, Trp) were statistically different than the HGF treated group (P 0.05

Some of the MITF target genes involved, such as IDH1 and NNT , are regulated through direct MITF binding to canonical enhancer box (E-BOX) sequences proximal to their promoters

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RNR was incubated with different concentrations of APR-246 or MQ for 30 min at 37 C followed by the addition of the reaction mixture

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