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The common therapeutic approach for these disorders is aimed at regulating circulating GH and IGF-1 levels using recombinant hormone therapy,8 but ongoing in vitro and in vivo studies are employing newer methods of treatment
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In humans, the bone effects of IGF-1 have been demonstrated in elderly women,113 where treatment with a low dose of recombinant IGF-1 led to increased osteoblast activity with only a minor increase in bone resorption, also decreased serum phosphate after 3 weeks

Ferroni, P
The outcome of fetal interactions with agents potentially teratogenic for the nervous system depends on the species and age of the fetus and the nature of the agent

Supporting children with autism through tailored nutritional strategies is vital, given their unique needs and common dietary challenges
