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Together, they help optimise GLP-1 activity, reduce cravings, and support healthy, sustainable weight management without the need for synthetic interventions

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For instance, TGR5 is expressed in rodent and human pancreatic islets and regulates insulin secretion (162)

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[DOI] [PubMed] [Google Scholar] 69.Morton GJ, Cummings DE, Baskin DG, Barsh GS, Schwartz MW