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Sometimes they are an incidental finding in otherwise normal brains at sporadic locations

Vijayakumar, B

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employed a chemotherapy-induced diarrhea (CID) mouse model and an IEC-6 cell model, and reported that non-replicative, heat-killed Bifidobacterium conferred protective effects by modulating the BCL2mediated mitochondrial apoptosis pathway, effectively alleviating diarrhea and suppressing intestinal epithelial apoptosis (Yan et al., 2025)

This indirect approach to immune modulation through gut health represents a complementary strategy rather than a direct treatment for lupus itself

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