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[DOI] [PubMed] [Google Scholar] Matsumoto J, Ogawa H, Maeyama R, Okudaira K, Shinka T, Kuhara T, Matsumoto I

A water-soluble tomato extract rich in secondary plant metabolites lowers trimethylamine-n-oxide and modulates gut microbiota: a randomized, double-blind, placebo-controlled cross-over study in overweight and obese adults

Data Extraction Two researchers read the full texts independently and extracted the following contents: publication data (first author's name, year of publication), study characteristic (study design, sample size, follow-up duration, inclusion criteria, and endpoints), patient characteristics (age, gender, NYHA classification, cardiac histology, and LVEF), treatment protocol (L-C dose), and outcome measures (all-cause mortality, overall efficacy, NYHA classification, 6-minute walk, LVEF, SV, CO, E/A, LVEDD, LVESD, LVESV, BNP, NT-proBNP, and adverse events)

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