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Jakubczyk K, Dec K, Kaduska J, Kawczuga D, Kochman J, Janda K

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A brittle nail sustaining damage from a light scratch (Source: Wikimedia Commons) Why Do Nails Change With Kidney Disease

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When the adrenal glands are overworked for extended periods, the cortisol they produce progressively reduces

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Microglia and neuropathic pain

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Notably, as a crucial cytosolic pattern recognition receptor, the NLRP3 inflammasome detects diverse stimuli, including microbial pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), while also responding to metabolic disturbances such as hyperglycemia and free fatty acids (Zangara et al., 2021)

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This technique not only helps eliminate the source of infection but also maximizes the preservation of pancreatic tissue (avoiding over-resection), thereby improving patients quality of life

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