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Jakubczyk K, Dec K, Kaduska J, Kawczuga D, Kochman J, Janda K

A brittle nail sustaining damage from a light scratch (Source: Wikimedia Commons) Why Do Nails Change With Kidney Disease

When the adrenal glands are overworked for extended periods, the cortisol they produce progressively reduces

Microglia and neuropathic pain

Notably, as a crucial cytosolic pattern recognition receptor, the NLRP3 inflammasome detects diverse stimuli, including microbial pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), while also responding to metabolic disturbances such as hyperglycemia and free fatty acids (Zangara et al., 2021)

This technique not only helps eliminate the source of infection but also maximizes the preservation of pancreatic tissue (avoiding over-resection), thereby improving patients quality of life
