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The data (Figure 3A) suggested a modest rise (~ 15%) in mean activity among replicate samples, but the sample-to-sample variation was large enough that statistical significance was not achieved ( p = 0.57)

Planta 251(2):43

Abbreviations AE: Adverse events AUC: Area under the plasma concentration time curve BID: Twice daily CI: Confidence interval CL: Clearance C max : Maximum observed plasma concentration COPD: Chronic obstructive pulmonary disease CS: Closed system CV%: Coefficient of variation DPI: Dry powder inhaler F: Fraction bioavailable FEV 1 : Forced expiratory volume in 1 s FVC: Forced vital capacity GLY: Glycopyrronium bromide GOLD: Global Initiative for Chronic Obstructive Lung Disease ICS: Inhaled corticosteroid IV: Intravenous LAMA: Long-acting muscarinic antagonist LS: Least squares PK: Pharmacokinetics pMDI: Pressurized metered dose inhaler SAE: Serious adverse event SD: Standard deviation t : Elimination half-life t max : Time to reach maximum plasma concentration V ss : Volume of distribution at steady state V z : Volume of distribution References Decramer M, Janssens W, Miravitlles M

Additionally, Suhayda & Walton (2002) highlight the role of healthcare professionals in managing fluid and electrolyte imbalances, particularly in older adults

Loguercio, C

Supplementation studies which have utilized exogenous forms of glutathione are not that common due to the poor ability of glutathione to stay intact throughout the cell with most of it being found to be degraded in the extracellular compartment[18]
