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The vials were emptied and ~ 5 mL dH2O was added to each vial

Although the exact mechanism by which GGT variability causes VT is not known, it is presumed that GGT may affect the occurrence of VT as a mechanism similar to how variability in blood pressure or blood sugar adversely affects arteriosclerosis 30,31

Modification of proteins by isoketal-containing oxidized phospholipids

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However, the dose-dependence of CIPN development appears to be specific to the chemotherapy agent or combination regimen used