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Mol Cancer Ther 2014;13:890-901

(2003) An imbalance in antioxidant defense affects cellular function: the pathophysiological consequences of a reduction in antioxidant defense in the glutathione peroxidase-1 (Gpx1) knockout mouse

Ulrich Ulrike H, Elizabeth MP, Xiao L, Curtin K, Duggan D, Hsu L, et al

Gastroenterology 131 , 11101121 (2006)

A 3-week swimming exercise regimen was shown to be protective and attenuate acute myocardial I/R injury in mice via the upregulation of PPAR, PPAR, and PGC1 and regulation of the genes involved in fatty acid and glucose metabolism and mitochondrial biogenesis

It means there are multiple entry points for supporting brain repair, and the right approach depends on the specific situation, whether acute injury, chronic degeneration, or proactive neuroprotection