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MPTP 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), a meperidine congener, was accidentally produced in the early 1980s during an impure synthesis of MPPP, which is an opioid analgesic drug (Davis et al., 1979

These findings suggest that, as with many other ROS sources, MAO-dependent ROS formation is beneficial up to a certain threshold and identify a dual, hormetic role for ROS produced by MAO-A

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Selenium: Biochemical Role as a Component of Glutathione Peroxidase

Zinc, when included, also contributes to immune cell development