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Many GERD patients take medications for other conditions that independently harm the gastrointestinal tract

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In addition, Caveolin-1 (Cav-1), a 21-kDa integral plasma membrane protein is a well-known negative regulator of eNOS activity in vascular endothelial cells 17,18,19,20,21,22

doi: 10.1200/JCO.2018.36.15_suppl.e21138 252 GoldbergSBSupkoJGNealJWMuzikanskyADigumarthySFidiasPet al

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Calves, Swine and Sheep: 5 mL per 100 pounds of body weight