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Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit

2.1.2 Role of SIRT1-p53 in ferroptosis p53 is a multifunctional protein that plays a crucial role in regulating intracellular levels of reactive oxygen species (ROS) and modulating ferroptosis through targeting downstream molecules (Ma et al., 2020)

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This dual action creates an optimal environment for the formation of new collagen and elastin