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Molecular Psychiatry , 18 , 12111217

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[19] Pernicious anemia [edit] Pernicious anemia is a disease caused by an autoimmune response that produces antibodies that attack the parietal cells in the stomach lining, preventing them from creating intrinsic factor needed for the absorption of vitamin B 12

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Treatment with the specific AMPK activator A769662 increases fatty acid oxidation and decreases activation of JNK, which is involved in inflammatory signaling 68

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Niacin-supplemented AD mice also had elevated expression of genes including Ctnnb1 , Mdm2 , and Pten , which are involved in processes such as Wnt signalling, posttranslational modifications, and regulation of mTOR signalling [155]

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