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Therefore, inhibition of PDK1 weakens the TCA cycle and shifts glucose metabolism from OXPHOS to glycolytic pathways (137)

Other sources of ROS include xanthine oxidase, uncoupled NO synthase, and others [61]
Omarigliptin Mitigates Lipopolysaccharide-Induced Neuroinflammation and Dysfunction of the Integrity of the Blood-Brain Barrier
10.1002/anie.201204935 61 LiJ.ShiJ.MedinaJ
Chalazonitis and Rao, 2018)

The 5-hydroxymethyl-2-furoic acid values were higher in patients exposed to mold vs the control patients (9.11 vs 2.91 mmol/mol of creatinine) (p value= 0.00075)