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By targeting these pathways, the polyphenols mitigate oxidative damage, prevent protein misfolding, and reduce neuroinflammation, offering significant therapeutic benefits for neurodegenerative and metabolic disorders

In pancreatic -cells, mitophagy-inducing compounds such as silibinin and cyanidin-3-O-glucoside (C3G) improve glucose metabolism and alleviate hyperglycemia

Enhancing Immune Function As we age, our immune system weakens

Furthermore, microneedles provide a minimally invasive method for delivering antioxidants to the deeper layers of the skin, enhancing treatment efficacy

Genetic variations in the activity of glutathione-S-transferase-4, a GSH-dependent enzyme that reduces 4hydroxynonenal, is a determining factor in the extent of neurodegeneration after TBI (Al Nimer et al., 2013)

[DOI] [PubMed] [Google Scholar] 97.Naowarojna N., Irani S., Hu W., Cheng R., Zhang L., Li X., et al