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In this context, a nanodrug delivery system (NDDS) has emerged as a promising approach for lung cancer treatment, offering distinct advantages such as targeted delivery, responsiveness to the tumor microenvironment, site-specific release, and enhanced induction of apoptosis in cancer cells, ultimately leading to tumor growth inhibition or even elimination

In human subjects, erythrocyte GPX1 activity is correlated with the risk of future cardiovascular events [86], and the Leu198 allele has been associated with increased risk of cardiovascular disease [8992]