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Allicin inhibits the growth of HONE-1 and HNE1 human nasopharyngeal carcinoma cells by inducing ferroptosis

Iwakura T, Takanashi S, Masuda A, et al

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The activated cPLA2 complex also binds to the lysosomal membrane and facilitates the release of enzymes that damage organelle membranes, leading to mitochondrial damage, organelle degradation and cell death associated with secondary injury [82]

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The CPBSN38L alone-treated group exhibited slight tumor cell-killing ability with an apoptosis rate of less than 5%, whereas the combination of CPBSN38L and US irradiation led to an excellent improvement in cell apoptosis, exhibiting an apoptosis rate of more than 90%