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How Semaglutide Injections Damage Blood Vessels When a needle penetrates the skin during a semaglutide injection, it can puncture small blood vessels (capillaries) in the subcutaneous tissue layer

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That distinction is the most important mechanistic lesson of the entire program

Once injected, it acts like a moisture reservoir, attracting and locking in water within your skin cells

Still, a mild deficiency will almost always get worse over time
