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Glutathione, a potent antioxidant naturally produced by the body, plays a crucial role in defending against oxidative stress and supporting immune function

Therefore, under such oxidative stress conditions, GSH reversibly binds to the thiol residues to prevent irreversible changes in proteins due to oxidative stress

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Sun et al., 2021)

They may damage important biomolecules, including lipids, proteins, and DNA (Lobo et al., 2010)

These observations highlight the need for additional prospective studies to evaluate the nuances regarding MMR-D heterogeneity as well as markers of resistance to inform future trials of combination therapies to further improve outcomes for patients with EC