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An increased incidence of myocardial infarction and stroke was found through analysis of data regarding the use of a COX-2 selective NSAID for the treatment of pain in the first 10 to 14 days after CABG surgery
Category 2 substances also have sufficient supporting information, but the FDA has identified significant safety risks
You can read simple resources from trusted healthcare providers that explain these topics in easy words.
There's no established tolerable upper intake limit from major health authorities
Insufficient levels of Vitamin B12 during pregnancy can trigger gastric troubles like constipation, acidity
That is the core distinction
