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Description
Repeated activation of the receptors can lead to upregulation and sensitization, causing hyperexcitability of the receptor even at low levels

The short answer: it depends on the peptides

Ilumets H, Rytil P, Demedts I, Brusselle GG, Sovijrvi A, Myllrniemi M, et al

(PubMed) Somasundaram S, Edmund NA, Moore DT, Small GW, Shi YY, Orlowski RZ

Supports muscle mass, bone density, and healthy body composition

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