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The oral formulation is the most significant differentiator: if an oral tablet can produce weight loss comparable to injectable CagriSema, it could fundamentally change how dual pathway obesity therapy is delivered

Choose Ozempic if: You want a time-tested drug, which has been known to work for both weight loss and diabetes if you are fine with weekly injections and require long-term dependency

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Iranian Journal of Public Health

Additionally, systemic side effects associated with sustained growth hormone stimulation include symptoms such as abnormal tissue growth, joint discomfort, and potential enlargement of the heart (cardiomegaly), Roberts says (21)

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