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It appears clear that the therapeutic potential of HO-1 in mediating the resolution of inflammation and tissue homeostasis may reside in specific phases of the inflammatory cascade and the regulation of hematopoietic output, thus calling for further study to fully characterize its therapeutic potential in different pathological contexts

[DOI] [PubMed] [Google Scholar] Koblan KS, Hopkins SC, Sarma K, Jin F, Goldman R, Kollins SH, Loebel A (2015) Dasotraline for the treatment of attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled, proof-of-concept trial in adults

Macrophages in tissue repair, regeneration, and fibrosis

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ROS is a key factor in the etiology of these pathologies (St-Pierre et al., 2006

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