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doi: 10.1111/j.1749-6632.2012.06538.x
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Perform a root-cause analysis of each observation, implement corrective and preventive actions (CAPA), submit a clear response to the FDA with timelines, and monitor effectiveness
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CDO1 is a nonheme iron metalloenzyme, transforming cysteine to taurine by catalyzing the oxidation of cysteine to its sulfinic acid, which prevents cytotoxicity from elevated cysteine levels (Stipanuk et al., 2009)
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