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This is assumed to be because hesperidins antioxidant nature allows it to scavenge reactive oxygen species (ROS) generated from mitochondria, subsequently preventing membrane damage caused by ROS [22]

Lastly, it is also worth mentioning that apart from reporting R 2 and Q 2 values as a measure of quality of a model, a receiver operating characteristic (ROC) plot of both training and overlaid test predictions is needed to claim utility of a particular predictive model

HIF-1 then translocates to the nucleus, where it binds to HIF-1 to form heterodimers

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The WCRF/AICR increased their efforts and recommendations after the first update of the WCRF/AICR guidelines in 2013, 14 recommending the creation of a Continuous Update Project that reports extensively across several cancer types using rigorous systematic review techniques