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Description
Some ferroptosis-targeting agents have poor pharmacokinetic properties, such as low solubility, high metabolic clearance, low cellular permeability, and short half-lives ( Figure 7 )
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The typical gradient was 10% to 40% component B over 30 minutes at a flow rate of 1 ml/min at 37C where component A was 80 mM triethy amine phosphate, pH 3.0 and component B was acetonitrile (ACN)
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