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Description
Advancements in pancreas-targeted delivery could enable therapies that restore endogenous glycemic control, representing a potential approach shift from the current reliance on exogenous insulin and other medications

Muramatsu T, Wang ZC, Fang YR, Hu KB, Yan H, Yamada K, et al

Effects of diabetes on microglial physiology: a systematic review of in vitro, preclinical and clinical studies

They are endogenously used in response to injury or disease to enhance neuron survival, axonal growth, synapse formation, and plasticity [268]

Peer review Peer review information Nature Metabolism thanks Joseph Baur, Claire Eyers and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Current UK law generally restricts all injectable products to POM status
